Revista Biomédica Revisada Por Pares
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Palabras clave: diabetic nephropathy, microvascular complications, chronic renal disease physiopathology
Chronic kidney disease is a common complication of diabetes. Its importance lies in its high prevalence and future projection. It is associated with high health costs and global cardiovascular deterioration as well. The development of this disease pathophysiology is being studied and it is known that a series of complex molecular pathways determining a microvascular disease are involved. This review addresses the known pathways in the development of diabetic nephropathy aiming to improve the understanding of potential therapeutic targets that could be developed in the future.
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Chronic kidney disease is a common complication of diabetes. Its importance lies in its high prevalence and future projection. It is associated with high health costs and global cardiovascular deterioration as well. The development of this disease pathophysiology is being studied and it is known that a series of complex molecular pathways determining a microvascular disease are involved. This review addresses the known pathways in the development of diabetic nephropathy aiming to improve the understanding of potential therapeutic targets that could be developed in the future.
Autores:
Carlos Eduardo Meza Letelier[1], Camilo Alfredo San Martín Ojeda[1], José Javier Ruiz Provoste[1], Cristobal Jesus Frugone Zaror[1]
Citación: Meza Letelier CE, San Martín Ojeda CA, Ruiz Provoste JJ, Frugone Zaror CJ. Pathophysiology of diabetic nephropathy: a literature review. Medwave 2017 Ene-feb;16(1):6839 doi: 10.5867/medwave.2017.01.6839
Fecha de envío: 28/10/2016
Fecha de aceptación: 12/12/2016
Fecha de publicación: 12/1/2017
Origen: no solicitado
Tipo de revisión: con revisión por tres pares revisores externos, a doble ciego
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