Medwave 2015;15(Suppl 2):e6287 doi: 10.5867/medwave.2015.6287
¿Cuál es el efecto de la kinesioterapia respiratoria en niños hospitalizados por neumonía?
What is the effect of chest physiotherapy in hospitalized children with pneumonia?
Felipe Damiani, Rodrigo Adasme
Abstract
Chest physiotherapy is applied in clinical practice for the treatment of pneumonia. However, its use is still controversial. Searching in Epistemonikos database, which is maintained by screening 30 databases, we identified one systematic review including two relevant randomized controlled trials. We combined the evidence using meta-analysis and generated a summary of findings table following the GRADE approach. We concluded it is unclear whether chest physiotherapy increases or decreases the length of hospitalization, severity, or the time to clinical improvement in children with pneumonia because the certainty of the evidence is very low.
Problem
Pneumonia is an acute inflammatory lung disease, affecting people at different ages worldwide. However, the most severe consequences and morbidity are related to young children and elderly subjects. Chest physiotherapy has been widely used for pediatric patients. The main goal of this therapy is to assist the clearance of bronchial secretions, maintain lung capacities and to improve clinical outcomes reducing airway resistance and work of breathing.
Methods
We used Epistemonikos database, which is maintained by screening more than 30 databases, to identify systematic reviews and their included primary studies. With this information, we generated a structured summary using a pre-established format, which includes key messages, a summary of the body of evidence (presented as an evidence matrix in Epistemonikos), meta-analysis of the total of studies, a summary of findings table following the GRADE approach and a table of other considerations for decision-making.
Key messages
- It is unclear whether chest physiotherapy increase or decrease the length of hospitalization, severity, or the time to clinical improvement in children with pneumonia because the certainty of the evidence is very low.
- There is a high probability of future evidence changing what we know about this question.
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About the body of evidence for this question
What is the evidence. See evidence matrix in Epistemonikos later
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We found only one systematic review [1] including two pertinent randomized controlled trials [2],[3].
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What types of patients were included
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The studies included hospitalized patients with pneumonia that were clinically stable for receiving chest physiotherapy.
Both baseline risk and pneumonia severity of patients were variable. Age ranged from 29 days to 12 years. |
What types of interventions were included
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Different types of chest physiotherapy were used. The first study applied standardized chest physiotherapy including positioning, thoracic vibration, thoracic compression, positive expiratory pressure, breathing exercises and forced exhalation with the glottis open or ’huffing’ [2].
The other study made postural drainage, thoracic squeezing, chest percussion, vibration, cough stimulation and secretions suctioning (if necessary)[3].
Frequency and duration of chest physiotherapy were variable. In the first study patients received it three times daily [2] and in the other study patients received it twice daily for 30 minutes each session [3]. All studies were compared with standard treatment (oxygen administration, antibiotics and fluids if necessary). |
What types of outcomes were measured
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Time to clinical resolution, hospital length of stay, arterial oxygen saturation, X-ray, lung auscultation, and cough duration.
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Summary of findings
The information on the effects of chest physiotherapy is based on two randomized trials including 177 patients. Both studies included hospital length of stay as an outcome. One study measured clinical severity [2] and one study considered time to clinical improvement [3].
- It is unclear whether chest physiotherapy increases or decreases hospital length of stay in children with pneumonia because the certainty of the evidence is very low.
- It is unclear whether chest physiotherapy increases or decreases the clinical severity of pneumonia in children with pneumonia because the certainty of the evidence is very low.
- It is unclear whether chest physiotherapy increases or decreases the time to clinical improvement in children with pneumonia because the certainty of the evidence is very low.
Other considerations for decision-making
To whom this evidence does and does not apply
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- This evidence can be applied in children between 29 days and 12 years old with clinical diagnosis of pneumonia of variable etiology (bacterial or viral) and who are hospitalized and in stable clinical condition to receive chest physiotherapy.
- This evidence cannot be aplied to newborns or intensive care unit patients.
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About the outcomes included in this summary
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- Outcomes included in this summary are those which had more information and those used in clinical guidelines.
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Balance between benefits and risks, and certainty of the evidence
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- We could not perform a proper risk/benefit assessment because there is uncertainty about the latter.
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What would patients and their doctors think about this intervention
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- Health proffesionals have a subjective perception of a positive effect of chest physiotherapy, especially in patients with bronchial hypersecretion and increased work of breathing.
- Chest physiotherapy use in non-responders does not seem to be supported by the evidence and is associated with costs. However, in settings where there are no resource constraints, some patients and doctors may be motivated to use an unproven therapy whose perception is generally positive. In these cases, it is particularly important to inform the patient about the certainty of the evidence.
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Resource considerations
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- Chest physiotherapy is associated with high cost, since a trained professional is required. It is not possible to estimate the cost/benefit because there is uncertainty about the latter.
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Feasibility and implementation |
- Chest physiotherapy is feasible in most hospitals due to proffessional presence in pediatric units. However, the insufficient relationship between number of patients and professional supply in each center must be considered.
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Differences between this summary and other sources
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- Conclusions obtained in this summary are consistent with the systematic review identified and the recommendations of the main clinical guidelines [4],[5], where the application of chest physiotherapy as coadjuntive treatment in patients with pneumonia is not recommended. However, some guidelines [6],[7], mention that it could improve physiological parameters such as respiratory rate and oxygenation in patients with bronchial hypersecretion.
- Clinical and epidemiological evidence about the uses of chest physiotherapy in pediatric respiratory patients must be considered since there are worldwide differences in chest physiotherapy technique.
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Could this evidence change in the future? |
- The probability of evidence changing in the future is high, due to the very low certainty of the evidence.
- It is likely that a new systematic review, or an update of the existing one, would provide additional information, since at least one ongoing randomized controlled study was identified [8].
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How we conducted this summary
Using automated and collaborative means, we compiled all the relevant evidence for the question of interest and we present it as a matrix of evidence.
Follow the link to access the interactive version: Chest physiotheraphy in hospitalized children with pneumonia
Notes
The upper portion of the matrix of evidence will display a warning of “new evidence” if new systematic reviews are published after the publication of this summary. Even though the project considers the periodical update of these summaries, users are invited to comment in Medwave or to contact the authors through email if they find new evidence and the summary should be updated earlier. After creating an account in Epistemonikos, users will be able to save the matrixes and to receive automated notifications any time new evidence potentially relevant for the question appears.
The details about the methods used to produce these summaries are described here http://dx.doi.org/10.5867/medwave.2014.06.5997.
Epistemonikos foundation is a non-for-profit organization aiming to bring information closer to health decision-makers with technology. Its main development is Epistemonikos database (www.epistemonikos.org).
These summaries follow a rigorous process of internal peer review.
Conflicts of interest
The authors do not have relevant interests to declare.
Esta
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Chest physiotherapy is applied in clinical practice for the treatment of pneumonia. However, its use is still controversial. Searching in Epistemonikos database, which is maintained by screening 30 databases, we identified one systematic review including two relevant randomized controlled trials. We combined the evidence using meta-analysis and generated a summary of findings table following the GRADE approach. We concluded it is unclear whether chest physiotherapy increases or decreases the length of hospitalization, severity, or the time to clinical improvement in children with pneumonia because the certainty of the evidence is very low.
Autores:
Felipe Damiani
[1,2], Rodrigo Adasme
[2,3]
Filiación:
[1] Programa Asistencia Ventilatoria No Invasiva (ANVI), Ministerio de Salud, Chile
[2] Proyecto Epistemonikos, Santiago, Chile
[3] Unidad de paciente crítico pediátrico, Pontificia Universidad Católica de Chile, Santiago, Chile
E-mail: lfdamiani@uc.cl
Correspondencia a:
[1] Facultad de Medicina
Pontificia Universidad Católica de Chile
Lira 63
Santiago Centro
Chile
Citación:
Damiani F, Adasme R.
What is the effect of chest physiotherapy in hospitalized children with pneumonia?. Medwave 2015;15(Suppl 2):e6287 doi: 10.5867/medwave.2015.6287
Fecha de publicación: 19/10/2015
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- Chaves GS, Fregonezi GA, Dias FA, Ribeiro CT, Guerra RO, Freitas DA, Pet al. Chest physiotherapy for pneumonia in children. Cochrane Database Syst Rev. 2013 Sep 20;9:CD010277. | CrossRef | PubMed |
- Lukrafka JL, Fuchs SC, Fischer GB, Flores JA, Fachel JM, Castro-Rodriguez JA. Chest physiotherapy in paediatric patients hospitalised with community-acquired pneumonia: a randomised clinical trial. Arch Dis Child. 2012 Nov;97(11):967-71. | CrossRef | PubMed |
- Paludo C, Zhang L, Lincho CS, Lemos DV, Real GG, Bergamin JA. Chest physical therapy for children hospitalised with acute pneumonia: a randomised controlled trial. Thorax. 2008 Sep;63(9):791-4. | CrossRef | PubMed |
- Bradley JS, Byington CL, Shah SS, Alverson B, Carter ER, Harrison C, et al. The management of community-acquired pneumonia in infants and children older than 3 months of age: clinical practice guidelines by the Pediatric Infectious Diseases Society and the Infectious Diseases Society of America. Clin Infect Dis. 2011 Oct;53(7):e25-76. | CrossRef | PubMed |
- Harris M, Clark J, Coote N, Fletcher P, Harnden A, McKean M, et al. British Thoracic Society guidelines for the management of community acquired pneumonia in children: update 2011. Thorax. 2011 Oct;66 Suppl 2:ii1-23. | CrossRef | PubMed |
- Luna CM, Monteverde A, Rodríguez A, Apezteguia C, Zabert G, Ilutovich S, et al. [Clinical guidelines for the treatment of nosocomial pneumonia in Latin America: an interdisciplinary consensus document. Recommendations of the Latin American Thoracic Society]. Arch Bronconeumol. 2005
Aug;41(8):439-56. | PubMed |
- Gobierno de Chile, Ministerio de Salud. Guía Clínica infección respiratoria aguda baja de manejo ambulatorio en menores de 5 años. Santiago, Chile: MINSAL; 2013. | Link |
- Morrow B. The use of chest physiotherapy in children hospitalised with pneumonia. Pan African Clinical Trials Registry PACTR201404000706382. 2013. [on line] | Link |
Chaves GS, Fregonezi GA, Dias FA, Ribeiro CT, Guerra RO, Freitas DA, Pet al. Chest physiotherapy for pneumonia in children. Cochrane Database Syst Rev. 2013 Sep 20;9:CD010277. |
CrossRef |
PubMed |
Lukrafka JL, Fuchs SC, Fischer GB, Flores JA, Fachel JM, Castro-Rodriguez JA. Chest physiotherapy in paediatric patients hospitalised with community-acquired pneumonia: a randomised clinical trial. Arch Dis Child. 2012 Nov;97(11):967-71. |
CrossRef |
PubMed |
Paludo C, Zhang L, Lincho CS, Lemos DV, Real GG, Bergamin JA. Chest physical therapy for children hospitalised with acute pneumonia: a randomised controlled trial. Thorax. 2008 Sep;63(9):791-4. |
CrossRef |
PubMed |
Bradley JS, Byington CL, Shah SS, Alverson B, Carter ER, Harrison C, et al. The management of community-acquired pneumonia in infants and children older than 3 months of age: clinical practice guidelines by the Pediatric Infectious Diseases Society and the Infectious Diseases Society of America. Clin Infect Dis. 2011 Oct;53(7):e25-76. |
CrossRef |
PubMed |
Harris M, Clark J, Coote N, Fletcher P, Harnden A, McKean M, et al. British Thoracic Society guidelines for the management of community acquired pneumonia in children: update 2011. Thorax. 2011 Oct;66 Suppl 2:ii1-23. |
CrossRef |
PubMed |
Luna CM, Monteverde A, Rodríguez A, Apezteguia C, Zabert G, Ilutovich S, et al. [Clinical guidelines for the treatment of nosocomial pneumonia in Latin America: an interdisciplinary consensus document. Recommendations of the Latin American Thoracic Society]. Arch Bronconeumol. 2005
Aug;41(8):439-56. |
PubMed |
Gobierno de Chile, Ministerio de Salud. Guía Clínica infección respiratoria aguda baja de manejo ambulatorio en menores de 5 años. Santiago, Chile: MINSAL; 2013. |
Link |
Morrow B. The use of chest physiotherapy in children hospitalised with pneumonia. Pan African Clinical Trials Registry PACTR201404000706382. 2013. [on line] |
Link |