Revista Biomédica Revisada Por Pares
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Palabras clave: antibacterial agents, latin america, epidemiology
Ever since antimicrobial activity was observed at the end of the XIX century and antibiotics were produced on a large scale in the ’40s, microorganisms have developed multiple resistance mechanisms, making treatment of infectious diseases difficult. For instance, several Gram-positive and Gram-negative bacteria lowered their sensitivity to ß-Lactam antibiotics as a result of their inadequate use and abuse. For this reason, microbial resistance to these drugs represents an increasing health problem in Latin America due to the emergence of drug-resistant bacterial strains. This review aims to summarize and analyze scientific literature reporting resistance to ß-lactam antibiotics in Latin America. We compiled scientific papers published during the last five years from PubMed, SciELO, and LILACS-BIREME. We found that: (i) it is common to identify resistance genes for ß-lactams in the soil and animal farms, and (ii) over 40% of strains isolated from clinical samples developed resistance against ß-lactam antibiotics.
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Ever since antimicrobial activity was observed at the end of the XIX century and antibiotics were produced on a large scale in the ’40s, microorganisms have developed multiple resistance mechanisms, making treatment of infectious diseases difficult. For instance, several Gram-positive and Gram-negative bacteria lowered their sensitivity to ß-Lactam antibiotics as a result of their inadequate use and abuse. For this reason, microbial resistance to these drugs represents an increasing health problem in Latin America due to the emergence of drug-resistant bacterial strains. This review aims to summarize and analyze scientific literature reporting resistance to ß-lactam antibiotics in Latin America. We compiled scientific papers published during the last five years from PubMed, SciELO, and LILACS-BIREME. We found that: (i) it is common to identify resistance genes for ß-lactams in the soil and animal farms, and (ii) over 40% of strains isolated from clinical samples developed resistance against ß-lactam antibiotics.
Autores:
María Fernanda Latorre-Barragan[1,2], Andrea Cristina Zurita-Leal[3], Marco Esteban Gudiño Gomezjurado[4]
Citación: Latorre-Barragan MF, Zurita-Leal AC, Gudiño Gomezjurado ME. ß-lactam antibiotics resistance in Latin American countries. Medwave 2019;19(10):e7729 doi: 10.5867/medwave.2019.10.7729
Fecha de envío: 29/7/2019
Fecha de aceptación: 21/10/2019
Fecha de publicación: 20/11/2019
Origen: No solicitado
Tipo de revisión: Revisado por cuatro pares revisores externos a doble ciego
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