Revista Biomédica Revisada Por Pares
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Palabras clave: dermatomyositis, paraneoplastic syndrome, small cell carcinoma
Dermatomyositis is an autoimmune inflammatory myopathy associated with dermatologic findings. Its association with neoplasms is widely reported and has been shown to be higher in lung cancer, particularly small-cell carcinoma, probably as it originates from neuroendocrine cell precursors, as well as breast and ovarian cancer. The low frequency of dermatomyositis makes it difficult to suspect the underlying lesions among the diagnostic possibilities of systemic diseases with cutaneous manifestations. Therefore, the high probability of a neoplasm should always be considered, with reports of up to 75% in the eastern population and about 40% in general. In this report, we present a rare case of dermatomyositis with lesions in a shawl-like distribution, as a symptomatic debut of a small cell lung carcinoma.
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Dermatomyositis is an autoimmune inflammatory myopathy associated with dermatologic findings. Its association with neoplasms is widely reported and has been shown to be higher in lung cancer, particularly small-cell carcinoma, probably as it originates from neuroendocrine cell precursors, as well as breast and ovarian cancer. The low frequency of dermatomyositis makes it difficult to suspect the underlying lesions among the diagnostic possibilities of systemic diseases with cutaneous manifestations. Therefore, the high probability of a neoplasm should always be considered, with reports of up to 75% in the eastern population and about 40% in general. In this report, we present a rare case of dermatomyositis with lesions in a shawl-like distribution, as a symptomatic debut of a small cell lung carcinoma.
Autores:
Herman Ahumada Piña[1], Luis Fuentes Cabrera[1], Rodrigo Selamé Glena[1], Daniel García Oneto[1], Andrea Jiménez Aguilar[1,2], Claudia Durán Herrera[1,2], Jorge Ávila Pérez[1,2], Maximiliano Cortés Latorre[1,2]
Citación: Ahumada Piña H, Fuentes Cabrera L, Selamé Glena R, García Oneto D, Jiménez Aguilar A, Durán Herrera C, et al. Dermatomyositis as the first manifestation of small cell carcinoma: case report and literature review. Medwave 2016 Nov;16(10):e6609 doi: 10.5867/medwave.2016.10.6609
Fecha de envío: 18/8/2016
Fecha de aceptación: 20/10/2016
Fecha de publicación: 15/11/2016
Origen: no solicitado
Tipo de revisión: con revisión por dos pares revisores externos, a doble ciego
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