Revista Biomédica Revisada Por Pares
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Palabras clave: chronic obstructive pulmonary disease, exacerbation, anemia
Background
The presence of anemia in chronic obstructive pulmonary disease is not an infrequent event. Exacerbations of this disease have been associated with an increase in mortality in these patients. It is not clear if the presence of anemia is associated with the risk of exacerbations.
Objective
To establish the association between anemia and the incidence of outcomes related to exacerbations of chronic obstructive pulmonary disease.
Methods
Analytical study of a dynamic or open concurrent prospective cohort of patients diagnosed with chronic obstructive pulmonary disease at two health care institutions in Cartagena, Colombia, between July 2010 and July 2011.
Results
43.9% had anemia at the start of follow-up. The cumulative incidence of exacerbations was 63% in the anemic vs. 55.5% in the non-anemic group. The cumulative incidence of recurrence of exacerbations was 30.4% in the anemic vs. 38.8% in the non-anemic group. The rate of hospitalizations for exacerbations was 30.4% in the anemic vs. 33.3% in the non-anemic group.
Conclusions
No significant association was established between anemia and the incidence of exacerbations of chronic obstructive pulmonary disease, the incidence of recurrence of first exacerbation, the rate of hospitalizations for chronic obstructive pulmonary disease exacerbations and the recurrence time of the first exacerbation of chronic obstructive pulmonary disease.
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Background
The presence of anemia in chronic obstructive pulmonary disease is not an infrequent event. Exacerbations of this disease have been associated with an increase in mortality in these patients. It is not clear if the presence of anemia is associated with the risk of exacerbations.
Objective
To establish the association between anemia and the incidence of outcomes related to exacerbations of chronic obstructive pulmonary disease.
Methods
Analytical study of a dynamic or open concurrent prospective cohort of patients diagnosed with chronic obstructive pulmonary disease at two health care institutions in Cartagena, Colombia, between July 2010 and July 2011.
Results
43.9% had anemia at the start of follow-up. The cumulative incidence of exacerbations was 63% in the anemic vs. 55.5% in the non-anemic group. The cumulative incidence of recurrence of exacerbations was 30.4% in the anemic vs. 38.8% in the non-anemic group. The rate of hospitalizations for exacerbations was 30.4% in the anemic vs. 33.3% in the non-anemic group.
Conclusions
No significant association was established between anemia and the incidence of exacerbations of chronic obstructive pulmonary disease, the incidence of recurrence of first exacerbation, the rate of hospitalizations for chronic obstructive pulmonary disease exacerbations and the recurrence time of the first exacerbation of chronic obstructive pulmonary disease.
Autores:
Pablo Andrés Miranda Machado[1], Iván Baños Álvarez[2], Hernando Guillermo Gaitán Duarte [3]
Citación: Miranda Machado PA, Baños Álvarez I, Gaitán Duarte HG. Association between anemia and chronic obstructive pulmonary disease exacerbations in Cartagena Colombia: a prospective cohort study. Medwave 2019;19(2):e7602 doi: 10.5867/medwave.2019.02.7602
Fecha de envío: 13/9/2018
Fecha de aceptación: 6/3/2019
Fecha de publicación: 26/3/2019
Origen: no solicitado
Tipo de revisión: con revisión por cuatro pares revisores externos, a doble ciego
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