Review article
Medwave 2015 Aug;15(7):e6239 doi: 10.5867/medwave.2015.07.6239
Occupational hazards and diseases among workers in the emergency services: narrative review of international literature and an approach to Chile
Rosa Jiménez Paneque, Juan Ricardo Pavés Carvajal
References | Download PDF |
To Download PDF must login.
Print | A(+) A(-) | Easy read

Abstract

BACKGROUND
Healthcare workers face the risk of accidents and illnesses related to their occupation. Psychological stress, exposure to communicable diseases and violence are perhaps the most significant ones. Workers in emergency services are more likely to be subjected to these risks than healthcare workers in other areas. This review aims to assess current international literature regarding this situation and more specifically the treatment that this issue has had in Chile.

METHODS
We based the review mainly on PubMed/MEDLINE. The general search strategy included the following keywords: health personnel, emergency medical services and occupational diseases combined with other specific words. We also reviewed the state of prevention for occupational hazards in the emergency services.

RESULTS
More than 70 studies addressing the issue of one or another occupational hazard in emergency services were detected. In Chile 12 studies refer to the issue of occupational risks in healthcare workers and at least two of them focus on emergency services.

CONCLUSIONS
The review evaluates the overall picture of the risks and illnesses of emergency services health workers but does not analyze each of the risks in depth. We recommend delving deeper into the issue of occupational hazards of emergency service healthcare workers in order to help improve and evaluate preventative measures.


 
Introduction

It is known that an employee of any profession or occupation may be subjected to the risk of disease or suffering a trauma related to his or her work. The branch of Medicine named Occupational Medicine or Occupational Health deals with these health problems.  Occupational health includes the study of diseases related to occupations, the job and the workplace, accidents that may occur during working hours or during transfer from or to the workplace or between tasks, and the risks of illness or injury present in the work environment.

The WHO on its website states that occupational health encompasses all aspects of health and safety in the workplace and focuses especially towards primary prevention of risks. Furthermore, the World Health Organization promotes the development of this area stating "... occupational health and welfare of the people who work are prerequisites for productivity and are important for socio-economic and sustainable development in general." [1]

The risks at work are diverse and spread across a wide range of levels of impact and likelihood of occurrence ranging from a low chance of getting a relatively minor ailment, to the highest risk of dying from an accident or illness related to the occupation.

Obvious and known are the risks of construction workers, members of crews of ships and aircraft, drivers of any kind of automotive transport, firefighters, police officers, workers in cement factories, people working exposed to the sun and other occupations that involve great risks of serious trauma or diseases directly related to their work conditions.

Health workers also face risks of accidents or diseases because of their occupation. In this area, some common and important risks are labeled. The psychological stress generated by dealing with sick people who expect the care they receive will improve their health; contagion due to handling infected people with communicable diseases; radiation exposure by the use of equipment and devices that emit X-rays; and contact with chemical or biological substances that may derive from sick patients. WHO mentions seven types of risks to which health workers are exposed: biological (such as hepatitis, tuberculosis and acquired immunodeficiency syndrome); chemicals (such as contact with glutaraldehyde and ethylene oxide); physical (like noise and radiation); ergonomic (e.g. heavy lifting): psychosocial (such as stress and violence), and related to fire, explosion and contact with electricity [2].

Workers in the emergency services are subject to almost all the risks of illness mentioned above probably more likely than workers in other areas of health care are. Stress, harmful biological substances and violence are perhaps the risks to which most often emergency department workers are exposed.

This review aims to assess concisely the magnitude of the problem from the international literature published without delving into the intricacies of its causes and consequences. For our location in Santiago, Chile, we will make a particular foray into this country.

Methods

We reviewed PubMed database that contains over 24 million citations of biomedical literature obtained from MEDLINE (database of the National Library of Medicine of the United States), magazines of life sciences and online books.

The general search strategy included the following descriptors obtained from Medical Subject Headings (MeSH) PubMed: health personnel, emergency medical services and occupational diseases.

So we generated a basic search strategy: (("Health Personnel"[Mesh]) AND "Emergency Medical Services"[Mesh]) AND "Occupational Diseases"[Mesh]) and further combined it with other keywords separately: stress, psychological; HIV; tuberculosis; workplace violence; human engineering and sleep disorders, circadian rhythm.

For the search of the published literature in Chile, we also explored the databases Scielo, LILACS and the general Google search data. We also looked for documents published by international organizations such as WHO and the International Labor Organization (ILO) on their websites; and for Chile, we looked for publications of the Ministry of Health as well.

We did not set a time limit to the search terms but emphasized that published in the last ten years.

For an easier reading of the review, the results are set out by risk explored.

Results

Stress (psychosocial risk)
The likelihood of stress is usually high in situations where patients' lives are at risk and the health care provider must operate with agility and skill. It is recognized that a worker with stress is "less likely to be healthy, is poorly motivated, less productive and less safe at work," a situation that also affects the success of the organization [3]. Stress is inherent to psychosocial factors that influence the work, an issue widely discussed at the ninth session of the joint committee ILO / WHO meeting in 1984 [4]. The literature reviewed, displays the issue of stress experienced by emergency service workers addressed by different authors and from different angles [5],[6],[7],[8],[9],[10],[11],[12],[13],[14],[15],[16]. It is very likely that stress be the number one occupational hazard for workers (doctors, other professionals, technicians and administrative employees) of the emergency services and its consequences are quite varied. Flowerdew et al [9] identify factors causing stress in a survey conducted in an emergency department of a London hospital and focused on staff behavior.  They identified as most important excess workload (due to shortage of staff in that service) and deficiencies in teamwork. Healy and Tyrrell [10] conducted a study on attitudes of doctors and nurses who were emergency department workers. These authors remark that witnessing aggression or violence and participating in the resuscitation of people, may trigger important emotional demands and, despite the frequency with which emergency service workers face them, they do not become immune to stress. In   a study conducted with emergency physicians in Germany, Pajonk et al, point out the importance of personality type in the consequences of stress as the so-called "post-traumatic stress disorder" [8]. In a study conducted in France [5] stress was associated with age younger than 30 years and low social support from supervisors. In addition, non-medical personnel had more stress-related problems than physicians.

Stress often also generates the syndrome called "burnout" which has also been and is being studied in professionals working in emergency departments [11],[14],[17],[18],[19],[20]. In a recent analysis carried out in the UK, stress is considered a sign and symptom of what they call "the emergency medicine workforce crisis” [21].

Bernaldo de Quiros-Aragon and Labrador-Encinas [6] found a moderate average level of stress and burnout in workers from emergency services in Madrid. Another study in Spain [7] states overwork and lack of emotional support are major predictors of burnout or any of its components. A study in nurses working in emergency services (hospital and pre-hospital) in Italy [18], finds that at least two thirds of nurses suffering from burnout classified as serious. The emergency service workers, showed a burnout level higher than that found in workers from intensive care units and palliative care in a study at a large hospital in Madrid [20].

Direct contact with blood or other biological fluids
Infection through contact with contaminated blood or body fluids is a problem in the emergency services, addressed by various studies reported in the literature [22],[23],[24],[25],[26],[27],[28]. These services often present situations where the necessary speed in caring for the sick, hampers taking precautions designed to prevent direct contact with blood or other biological fluids. We highlight needlestick or other injuries caused by sharp instruments when there is a risk of contamination from blood of patients with human immunodeficiency virus (HIV), hepatitis C or B or other disease.

Several studies in the 90s assess the risk of infection by human immunodeficiency virus in the emergency service workers [23],[24],[26]. One of these studies [23] situates the annual risk of infection by human immunodeficiency virus in doctors or nurses in emergency departments between 0.0005% and 0.026%, a low level of occurrence, but with high impact if one considers the consequences of an infection such as the human immunodeficiency virus.

The emergency department of a hospital in Rhode Island, United States, received 1436 visits classified as exposures to blood or other fluids [22] between 1995 and 2001. Twenty two percent of these visits were from health workers and 73% of the latter were needle sticks or sharps injuries. The needle puncture was the most frequent type of occupational exposure in hospital workers in a recent study in Tanzania as well [25].

In a study conducted in 2012 in Tehran, with 200 workers in the emergency services of three hospitals, it was reported that 115 (57.5%) had at least one episode of exposure to blood or accident with needle or other sharp instrument during their work in the emergency department [29]. An editorial of the Venezuelan journal Salud de los Trabajadores notes that about two million needlestick accidents are reported each year worldwide and it is presumed that, as many remain unreported [30].

Infection with diseases such as tuberculosis are also considered more likely in emergency departments´ workers. In 1994, the results of a survey conducted in the emergency department at Harbor-UCLA Medical Center (University of California, Los Angeles, United States) reveal that 25 of the 81 (31%) workers who responded to the survey and who had not received the BCG vaccine became positive to tuberculin test (Mantoux) during the time they worked in this department [31].

In 2011, a study conducted between 2007 and 2009 in urban emergency services from Boston (Massachusetts, USA), positioned tuberculosis exposure in second place, after meningitis, with 17.2% of all reports. This study also mentions exposure to other infectious diseases such as influenza [32].

Violence
Another health risk that is high in emergency service workers is violence. Very often situations occur where the relatives of patients in critical condition, or the patients themselves in stress situations, physically assault health providers or provoke episodes of violence that somehow involve health workers. A recent review of the literature highlights the problem of violence in emergency departments and its consequences for the health of their workers. The authors conclude that the problem is similar in many regions of the world and universal measures should be taken to prevent it [33]. In 1998, a survey in Canada reported that over 90% of workers had experienced verbal or physical violence during their working time in the emergency department. In the same survey, 68% referred they perceived an increase in the frequency of violence in the time and 27% had to take leave from work due to an episode of violence [34].

An editorial in the journal International Orthopaedics published in 2013, discusses with emphasis the current problem of violence against health workers. It criticizes the problem of violence against health workers in places where armed conflicts take place but it also states that violence "due to drug use, ignorance, intolerance and disrespect has become a daily occurrence." The editorial notes that there is no country free from this type of violence and pinpoints workers from the emergency departments at the forefront of danger regarding this scourge [35].

Other studies have examined violence in the emergency services and their impact on the people who work in them [36],[37]. A study conducted in an Italian hospital that included repeated surveys: 2005, 2007 and 2009, reports emergency departments as the most affected by violence that particularly involves doctors and nurses [38]. Miret and Martínez-Larrea point out thirteen factors that may contribute to the development of violence in emergency services; ten possible effects of violence on workers in these services; and eight effects of this problem on the services themselves [14].

Other risks
The literature mentions and discusses other occupational hazards for workers in the emergency services. Disorders involving the musculoskeletal system are frequent in health workers in general, particularly in nurses. Carrying stretchers with patients has been studied as a factor that produces high levels of fatigue in ambulance workers [39],[40]. A Finnish study published in 2008, found that handling heavy loads, maintaining unhealthy habits, and sleep disorders were factors associated with the occurrence of low back pain; three circumstances commonly seen in emergency services workers [41]. Furthermore, musculoskeletal disorders, burnout and job demands were interrelated factors in a study with nurses from the emergency services [42].

Exposure to toxic chemicals is one of the seven issues WHO points as risks for health workers [2]. An eloquent example of this risk is the case of a patient (published in 2004) who ingested arsenic and how several doctors who treated him in the emergency department, developed laryngitis and disorders such as corneal erosions due to the exposure to toxic gases derived from arsenic [43]

Another aspect that affects workers in the emergency services is the change in shift work and night work. Many workers in the emergency services are often required to work on different schedules. A very recent study explains why the disruption of the biological clock actually may have a negative impact on health and thus endorses clinical studies that have linked this problem to the risk of some diseases (metabolic, neurological disorders and cancer) [44]. The increased risk of cancer, particularly breast cancer, due to working night shifts is still under study [45],[46],[47],[48],[49],[50]. Four recent meta-analysis found a weak but consistent association between night work and breast cancer risk [46],[47],[49],[50]. While more studies are needed, the results so far point to a relative risk (relative to those who do not work night shifts) relatively low but above one. The meta-analysis by Jia et al gives overall confidence interval for the relative risk of breast cancer (risk for persons performing night shifts / risk for people who do not do night shifts) of 1.08 to 1.33 [50].

Night work has also been associated with other disorders. A recent systematic review definitively links it to the risk of metabolic syndrome when it finds a 95% confidence interval for the relative risk for those who had a longer exposure to work at nighttime with regard to night work not performed between 1.39 and 1.49 [51].

Prevention
Recognition of the risks experienced by workers in the emergency services has also contributed to the development of prevention measures and programs. In 2002 the ILO conjointly with WHO published the "Framework guidelines for addressing workplace violence in the health sector" [52]. In 2007, another joint work of both organizations resulted in a document that regulates the post-exposure prophylaxis to human immunodeficiency virus, HIV [53].

WHO has also developed the guiding principles to ensure injection device security [54]. An article recently published, addresses and analyzes the prevention of burnout stress syndrome in emergency service workers in [55]. The author notes that the emergency services often work beyond their capabilities and have fewer resources than necessary; this fact is reflected in the mental health of their workers and leads to low survival in their jobs. He further notes the importance of designing prevention strategies that address a wide range of aspects leading to maintain wellness in the workplace. The College of Emergency Medicine published on its website in October 2013 the results of a survey in which they evaluate the sustainability of emergency services in the UK. The results led to the publication of three key recommendations for a prevention strategy [56].

The global plan of action developed by WHO includes the need for hepatitis B vaccination of health workers [57]. The Institute of Public Health, Ministry of Health, Government of Chile, on its website on biological agents, publishes preventive guidelines for handling potentially toxic or harmful biological substances [58]. Furthermore, the Ministry of Health, Government of Chile, published in 2012 a document entitled "Protocols for monitoring workers exposed to risk factors of skeletal muscle of upper limb disorders related to work" “Protocolos de vigilancia para trabajadores expuestos a factores de riesgo de trastornos musculo esqueléticos de extremidades superiores relacionados con el trabajo” [59].

However, some studies point out poor adherence to safety measures at work observed in the emergency services workers. A recent review of the literature recognizes poor adherence to the practices for infection control as well [60]. Another study, in the Netherlands, also reported problems in adherence to post-exposure tetanus prophylaxis [61]. A survey of workers from an emergency hospital in Nigeria recently evaluated the attitude toward hepatitis B vaccine in emergency services [62]. Contradictorily, even though more than 80% of respondents knew about hepatitis B vaccine and the disease, only 25% were vaccinated.

Chile
The literature on health and occupational risk in workers of the emergency services is not very abundant in Chile; nevertheless, we must highlight some studies and published papers. In 1999, Alvarado et al [63] conducted a comprehensive analysis of the situation of occupational health in Chile at that time, including weaknesses, strengths and projections. In 2008, Melita et al studied the presence of job stress (burnout) and its probable relationship to social and employment factors, in nurses who worked in emergency units and emergency healthcare services in the Eighth Region [64]. They surveyed 88 nurses and found a moderate average degree of burnout according to the best-known instrument to measure this disorder. A thesis presented for the degree of Bachelor of Midwifery addresses job stress in the staff of emergency obstetric and gynecological unit of the Regional Clinical Hospital of Valdivia [65].

More publications come from studies that address occupational hazards in health workers without special attention to emergency services. A study on job stress and health in persons who worked in primary care (professionals or not) in a commune located in the metropolitan region [66] was published in 2006. The prevalence of burnout in the Clínica Alemana of Puerto Varas was the subject of a study published in 2010 [67]. In 2006, another study on the prevalence of burnout is published, this time in an intensive care unit of Concepción [68]. In 2004, violence perceived by workers of a primary care clinic in Region VIII [69] is studied. Ceballos et al, recently conducted a review of psychosocial risks at work with particular attention to nurses [70]. Sanchez published in 2004 an article reviewing risk prevention in health personnel [71]. Rojas et al published in 2008 a study about accidents reported in workers at the Clinical Hospital of the University of Chile, the University Psychiatric Clinic, Quilín Clinic and Medical Centers Badajoz, El Salto, Macul and Vivaceta [72]. A thesis of the School of Kinesiology, University of Chile, studied ergonomic hazards in nursing assistants and auxiliary personnel from two units at the General Hospital of the University of Chile [73]. A thesis of the Austral University of Chile presents the psychosocial risk factors related to stress in nurses who work in critical services in Puerto Montt Hospital [74]. A study about occupational mental health of nurses in the public sector in the Metropolitan Region [75] was presented in 2007 at the "International Seminar on research, policies and practices associated with mental health and work in Chile: a gender perspective". Recently the Chilean Medical Journal (Revista Médica de Chile) published a study, carried out with workers of a highly complex pediatric hospital, where the authors describe the association between psychosocial risk factors in the workplace and various mental health indicators [76].

The annex provides a summary of relevant quantitative data that emerged from the literature review.

Final considerations

Services and emergency departments of hospitals, clinics and primary care, are essential in a health system. This is due to the frequency of accidents and the incidence of disease episodes that need immediate care in any population in the world. The results of the review suggest that, within the diverse group of people who work in and for health systems, those working at emergency services are the most exposed to occupational hazards such as major stress, communicable diseases and violence. This is an issue of concern for health systems worldwide, due to the importance of emergency services for the health of populations. Similarly, its relevance also derives from the negative impact that unawareness of this problem would have on the services themselves and their workers (doctors, nurses and other professionals, technicians or administrative personnel). 

In Chile, one can also perceive evidence of the general problem, but still appears little explored. In its present condition, as a country that aspires to improve its health system in short time, a more substantial and thorough study of this problem is warranted. 

Finally, although the topic is generously discussed in the literature, it still not seems to be a closed issue. For instance, risks related to night work and violence continue to be studied and evaluated. These aspects can vary between places and times. This means that, on the one hand, local studies are needed and secondly, only the repeatability of results at different latitudes will allow generalizations for a relevant completed knowledge. Moreover, it seems advisable in future studies to incorporate a gender perspective, given the high percentage of women who make up the health personnel at all levels. 

Recommendations

This review can assess the overall picture of the risks and illnesses of the emergency services, but does not allow the depth deserved by every one of the risks mentioned here. One must continue conducting studies on this subject, seeking accurate and precise estimates of the incidence of accidents and violence and prevalence of occupational diseases in this sector. It is also in order to assess risk and protective factors with more conceptual and methodological rigor. This will help to enrich prevention measures, evaluate their compliance and the factors that can prevent it as well as the efficiency and effectiveness of general or specific measures that can be implemented.

Notes

Annexx 1: Quantitative summary of occupational hazards in emergency service workers obtained from the review.

Conflicts of interests
The authors have completed the ICMJE Conflict of Interest form and have no relevant interests to declare. The forms may be requested from the author or the editors.

From the editor
This article was originally submitted in Spanish and was translated into English by the authors. The Journal has not copyedited this version.

Licencia Creative Commons Esta obra de Medwave está bajo una licencia Creative Commons Atribución-NoComercial 3.0 Unported. Esta licencia permite el uso, distribución y reproducción del artículo en cualquier medio, siempre y cuando se otorgue el crédito correspondiente al autor del artículo y al medio en que se publica, en este caso, Medwave.

 

ANTECEDENTES
Los trabajadores de la salud se enfrentan a riesgos de accidentes y enfermedades relacionados con su ocupación. El estrés psíquico, el contacto con enfermedades transmisibles y la violencia son quizás los principales riesgos. Los trabajadores de los servicios de urgencia están sometidos a ellos, con mayor frecuencia que los de otras áreas. La presente revisión tiene por objetivo evaluar el estado del tema en la literatura internacional, y en particular el tratamiento que a este tema se le ha dado en Chile.

MÉTODOS
Se revisó principalmente la base de datos PubMed de MEDLINE. La estrategia de búsqueda general incluyó las palabras clave: health personnel, emergency medical services y occupational diseases combinadas con otras más específicas. Se revisó también el estado de la prevención de riesgos laborales en los servicios de urgencia.

RESULTADOS
Se detectaron más de 70 estudios que abordaban el tema de uno u otro riesgo laboral en servicios de urgencia. En Chile se detectan 12 estudios que tocan el tema de riesgos laborales en trabajadores de la salud, al menos dos de ellos abordan los servicios de urgencia.

CONCLUSIONES
La presente revisión permite valorar el panorama general de los riesgos y enfermedades laborales de los servicios de urgencia, pero no permite la profundidad que amerita cada uno de los riegos mencionados aquí. Se recomienda continuar profundizando en el tema de los riesgos laborales de los trabajadores de los servicios de urgencia, con el fin de contribuir a perfeccionar las medidas de prevención y evaluar sus resultados.

Authors: Rosa Jiménez Paneque[1], Juan Ricardo Pavés Carvajal[1]

Affiliation:
[1] Medwave Estudios Limitada, Santiago, Chile
Author address:
[1] Villaseca 21
Of.702
Ñuñoa
Santiago
Chile

Citation: Jiménez Paneque R, Pavés Carvajal JR. Occupational hazards and diseases among workers in emergency services: a literature review with special emphasis on Chile. Medwave 2015 Aug;15(7):e6239 doi: 10.5867/medwave.2015.07.6239

Submission date: 5/8/2015

Acceptance date: 24/8/2015

Publication date: 8/9/2015

Origin: not requested

Type of review: reviewed by three external peer reviewers, double-blind

PubMed record

Comments (0)

We are pleased to have your comment on one of our articles. Your comment will be published as soon as it is posted. However, Medwave reserves the right to remove it later if the editors consider your comment to be: offensive in some sense, irrelevant, trivial, contains grammatical mistakes, contains political harangues, appears to be advertising, contains data from a particular person or suggests the need for changes in practice in terms of diagnostic, preventive or therapeutic interventions, if that evidence has not previously been published in a peer-reviewed journal.

No comments on this article.


To comment please log in

Medwave provides HTML and PDF download counts as well as other harvested interaction metrics.

There may be a 48-hour delay for most recent metrics to be posted.

  1. World Health Organization. Global strategy on occupational health for all: The way to health at work. Recommendation of the second meeting of the WHO Collaborating Centres in Occupational Health, Beijing, China,11-14 October 1994. | Link |
  2. World Health Organization. Health workers. Health worker occupational health. who.int [on line]. | Link |
  3. Leka S, Griffiths A, Cox T. Work Organization and stress: systematic problem approaches for employers, managers and trade union representatives / Protecting Workers’ Health Series No. 3. Geneva:WHO; 2004. | Link |
  4. Psychosocial factors at work: Recognition and control Report of the Joint ILO/WHO Committee on Occupational Health. Ninth Session Geneva, 18-24 September, 1984. | Link |
  5. Chakroun WO, Rejeb I, Kammoun L, Nasri A, Ghnainia T, Chaari A, Ksibi H, Chaari A, Bouaziz M, Rekik N. [Evaluation of stress among emergency staff: survey in a Tunisian emergency department]. Ann Fr Anesth Reanim. 2013 Sep;32(9):565-71. | CrossRef | PubMed |
  6. de Quirós-Aragón MB, Labrador-Encinas FJ. Evaluación del estrés laboral y burnout en los servicios de urgencia extrahospitalaria. International Journal of Clinical and Health Psychology. 2007;7(2):323-335. | Link |
  7. García-Izquierdo M, Ríos-Rísquez MI. The relationship between psychosocial job stress and burnout in emergency departments: an exploratory study. Nurs Outlook. 2012 Sep-Oct;60(5):322-9. | CrossRef | PubMed |
  8. Pajonk FG, Cransac P, Müller V, Teichmann A, Meyer W. Trauma and stress-related disorders in German emergency physicians: the predictive role of personality factors. Int J Emerg Ment Health. 2012;14(4):257-68. | PubMed |
  9. Flowerdew L, Brown R, Russ S, Vincent C, Woloshynowych M. Teams under pressure in the emergency department: an interview study. Emerg Med J. 2012 Dec;29(12):e2. | CrossRef | PubMed |
  10. Healy S, Tyrrell M. Stress in emergency departments: experiences of nurses and doctors. Emerg Nurse. 2011 Jul;19(4):31-7. | PubMed |
  11. Angius P, Campana G, Cattari F, Cattari M, Pirastru S, Tintori A, Serra A. [Burnout in emergency health care workers]. G Ital Med Lav Ergon. 2011 Jul-Sep;33(3 Suppl):339-42. | PubMed |
  12. Wu H, Sun W, Wang L. Factors associated with occupational stress among Chinese female emergency nurses. Emerg Med J. 2012 Jul;29(7):554-8. | CrossRef | PubMed |
  13. Adriaenssens J, De Gucht V, Van Der Doef M, Maes S. Exploring the burden of emergency care: predictors of stress-health outcomes in emergency nurses. J Adv Nurs. 2011 Jun;67(6):1317-28. | CrossRef | PubMed |
  14. Miret C, Martínez-Larrea A.. [The professional in emergency care: aggressiveness and burnout]. An Sist Sanit Navar. 2010;33 Suppl 1:193-201. | PubMed |
  15. Okada N, Ishii N, Nakata M, Nakayama S. Occupational stress among Japanese emergency medical technicians: Hyogo Prefecture. Prehosp Disaster Med. 2005 Mar-Apr;20(2):115-21. | PubMed |
  16. McPherson S, Hale R, Richardson P, Obholzer A. Stress and coping in accident and emergency senior house officers. Emerg Med J. 2003 May;20(3):230-1. | PubMed |
  17. Gillespie M, Melby V. Burnout among nursing staff in accident and emergency and acute medicine: a comparative study. J Clin Nurs. 2003 Nov;12(6):842-51. | PubMed |
  18. Cicchitti C, Cannizzaro G, Rosi F, Maccaroni R, Menditto VG. [Burnout syndrome in pre-hospital and hospital emergency. Cognitive study in two cohorts of nurses]. Recenti Prog Med. 2014 Jul-Aug;105(7-8):275-80. | CrossRef | PubMed |
  19. Escribà-Agüir V, Martín-Baena D, Pérez-Hoyos S. Psychosocial work environment and burnout among emergency medical and nursing staff. Int Arch Occup Environ Health. 2006 Nov;80(2):127-33. | PubMed |
  20. Casado Moragóna A, Muñoz Durána G, Ortega González N, Castellanos Asenjob A. [Burnout in professionals belonging to palliative, intensive care and emergency services in a general hospital]. Med Clin (Barc). 2005 Apr 16;124(14):554-5. | PubMed |
  21. Reynard K, Brown R. A clinical analysis of the emergency medicine workforce crisis. Br J Hosp Med (Lond). 2014 Nov;75(11):612-6. | CrossRef | PubMed |
  22. Merchant RC, Becker BM, Mayer KH, Fuerch J, Schreck B. Emergency department blood or body fluid exposure evaluations and HIV postexposure prophylaxis usage. Acad Emerg Med. 2003 Dec;10(12):1345-53. | PubMed |
  23. Marcus R, Culver DH, Bell DM, Srivastava PU, Mendelson MH, Zalenski RJ, et al. Risk of human immunodeficiency virus infection among emergency department workers. Am J Med. 1993 Apr;94(4):363-70. | PubMed |
  24. Kelen GD. Human immunodeficiency virus and the emergency department: risks and risk protection for health care providers. Ann Emerg Med. 1990 Mar;19(3):242-8. | PubMed |
  25. Mashoto KO, Mubyazi GM, Makundi E, Mohamed H, Malebo HM. Estimated risk of HIV acquisition and practice for preventing occupational exposure: a study of healthcare workers at Tumbi and Dodoma Hospitals, Tanzania. BMC Health Serv Res. 2013 Sep 30;13:369. | CrossRef | PubMed |
  26. De Carli G, Puro V, Binkin NJ, Ippolito G. Risk of human immunodeficiency virus infection for emergency department workers. Italian Study Group on Occupational Risk of HIV Infection. J Emerg Med. 1994 Nov-Dec;12(6):737-44. | PubMed |
  27. Kato-Maeda M, Ponce-de-León S, Sifuentes-Osornio J, Rangel-Frausto MS, Calva-Mercado J, Infante-Surez L, et al. Bloodborne viral infections in patients attending an emergency room in Mexico City: estimate of seroconversion probability in healthcare workers after an occupational exposure. Infect Control Hosp Epidemiol. 2000 Sep;21(9):600-2. | PubMed |
  28. Marcus R, Srivastava PU, Bell DM, McKibben PS, Culver DH, Mendelson MH, Zalenski RJ, Kelen GD. Occupational blood contact among prehospital providers. Ann Emerg Med. 1995 Jun;25(6):776-9. | PubMed |
  29. Galíndez L, Rodríguez Y. Riesgos Laborales de los Trabajadores de la Salud (Editorial). Salud de los Trabajadores. 2007;15(1):67-69. | Link |
  30. arsi D, Zare MA, Hassani SA, Abbasi S, Emaminaini A, Hafezimoghadam P, Rezai M. Prevalence of occupational exposure to blood and body secretions and its related effective factors among health care workers of three Emergency Departments in Tehran. J Res Med Sci. 2012 Jul;17(7):656-61. | PubMed |
  31. Sokolove PE, Mackey D, Wiles J, Lewis RJ. Exposure of emergency department personnel to tuberculosis: PPD testing during an epidemic in the community. Ann Emerg Med. 1994 Sep;24(3):418-21. | PubMed |
  32. El Sayed M, Kue R, McNeil C, Dyer KS. A descriptive analysis of occupational health exposures in an urban emergency medical services system: 2007-2009. Prehosp Emerg Care. 2011 Oct-Dec;15(4):506-10. | CrossRef | PubMed |
  33. Baydin A, Erenler AK. Workplace violence in emergency department and its effects on emergency staff. Int J Emerg Ment Health. 2014;16(2):288-90. | PubMed |
  34. Fernandes CM, Bouthillette F, Raboud JM, Bullock L, Moore CF, Christenson JM, Grafstein E, Rae S, Ouellet L, Gillrie C, Way M. Violence in the emergency department: a survey of health care workers. CMAJ. 1999 Nov 16;161(10):1245-8. | PubMed |
  35. Hinsenkamp M. Violence against healthcare workers. Int Orthop. 2013 Dec;37(12):2321-2. | CrossRef | PubMed |
  36. Lancman S, Mângia EF, Muramoto MT. Impact of conflict and violence on workers in a hospital emergency room. Work. 2013;45(4):519-27. | CrossRef | PubMed |
  37. Ferns T. Violence in the accident and emergency department--an international perspective. Accid Emerg Nurs. 2005 Jul;13(3):180-5. | PubMed |
  38. Magnavita N, Heponiemi T. Violence towards health care workers in a Public Health Care Facility in Italy: a repeated cross-sectional study. BMC Health Serv Res. 2012 May 2;12:108. | CrossRef | PubMed |
  39. Barnekow-Bergkvist M, Aasa U, Angquist KA, Johansson H. Prediction of development of fatigue during a simulated ambulance work task from physical performance tests. Ergonomics. 2004 Sep 15;47(11):1238-50. | PubMed |
  40. Aasa U, Angquist KA, Barnekow-Bergkvist M. The effects of a 1-year physical exercise programme on development of fatigue during a simulated ambulance work task. Ergonomics. 2008 Aug;51(8):1179-94. | CrossRef | PubMed |
  41. Miranda H, VViikari-Juntura E, Punnett L, Riihimäki H.. Occupational loading, health behavior and sleep disturbance as predictors of low-back pain. Scand J Work Environ Health. 2008 Dec;34(6):411-9. | PubMed |
  42. Sorour AS, El-Maksoud MM. Relationship between musculoskeletal disorders, job demands, and burnout among emergency nurses. Adv Emerg Nurs J. 2012 Jul-Sep;34(3):272-82. | CrossRef | PubMed |
  43. Kinoshita H, Hirose Y, Tanaka T, Yamazaki Y. Oral arsenic trioxide poisoning and secondary hazard from gastric content. Ann Emerg Med. 2004 Dec;44(6):625-7. | PubMed |
  44. West AC, Bechtold DA. The cost of circadian desynchrony: Evidence, insights and open questions. Bioessays. 2015 Jul;37(7):777-88. | CrossRef | PubMed |
  45. Kamdar BB, Tergas AI, Mateen FJ, Bhayani NH, Oh J. Night-shift work and risk of breast cancer: a systematic review and meta-analysis. Breast Cancer Res Treat. 2013 Feb;138(1):291-301. | CrossRef | PubMed |
  46. Wang F, Yeung KL, Chan WC, Kwok CC, Leung SL, Wu C, et al. A meta-analysis on dose-response relationship between night shift work and the risk of breast cancer. Ann Oncol. 2013 Nov;24(11):2724-32. | CrossRef | PubMed |
  47. Ijaz S, Verbeek J, Seidler A, Lindbohm ML, Ojajärvi A, Orsini N, et al. Night-shift work and breast cancer--a systematic review and meta-analysis. Scand J Work Environ Health. 2013 Sep 1;39(5):431-47. | PubMed |
  48. Rabstein S, Harth V, Pesch B, Pallapies D, Lotz A, Justenhoven C, et al. Night work and breast cancer estrogen receptor status--results from the German GENICA study. Scand J Work Environ Health. 2013 Sep 1;39(5):448-55. | PubMed |
  49. Megdal SP, Kroenke CH, Laden F, Pukkala E, Schernhammer ES. Night work and breast cancer risk: a systematic review and meta-analysis. Eur J Cancer. 2005 Sep;41(13):2023-32. | PubMed |
  50. Jia Y, Lu Y, Wu K, Lin Q, Shen W, Zhu M, Huang S, Chen J. Does night work increase the risk of breast cancer? A systematic review and meta-analysis of epidemiological studies. Cancer Epidemiol. 2013 Jun;37(3):197-206. | CrossRef | PubMed |
  51. Wang F, Zhang L, Zhang Y, Zhang B, He Y, Xie S, et al. Meta-analysis on night shift work and risk of metabolic syndrome. Obes Rev. 2014 Sep;15(9):709-20. | CrossRef | PubMed |
  52. Organización Internacional del Trabajo, Consejo Internacional de Enfermeras, Organización Mundial de la Salud, Internacional de Servicios Públicos. Directrices marco para afrontar la violencia laboral en el sector de la salud. Ginebra, Organización Internacional del Trabajo; 2002. | Link |
  53. World Health Organization. Post-exposure prophylaxis to prevent HIV infection: joint WHO/ILO guidelines on post-exposure prophylaxis (PEP) to prevent HIV infection. ISBN 978 92 4 159637 4 (NLM classification: WC 503.6); 2007. | Link |
  54. World Health Organization. Guiding principles to ensure injection device security. Safe Injection Global Network (SIGN) Secretariat. Department of Essential Health Technologies. WHO;2012. | Link |
  55. Hassan TB. Sustainable working practices and minimizing burnout in emergency medicine. Br J Hosp Med (Lond). 2014 Nov;75(11):617-9. | CrossRef | PubMed |
  56. Hassan TB, Walker B, Harrison M, Rae F. Stretched to the limit. A survey of Emergency Medicine consultants in the UK. The College of Emergency Medicine. October; 2013. | Link |
  57. World Health Organization. Workers’ health: global plan of action. Geneva: WHO; 2007. | Link |
  58. Instituto de Salud Pública, Ministerio de Salud, Gobierno de Chile. Agentes Biológicos. Ispch.cl [on line]. | Link |
  59. Departamento de Salud Ocupacional, Subsecretaria de Salud Pública, Ministerio de Salud, Chile. Protocolos de vigilancia para trabajadores expuestos a factores de riesgo de trastornos musculoesqueléticos de extremidades superiores relacionados con el trabajo. División de políticas públicas saludables y promoción. Departamento De Salud Ocupacional. Santiago-Chile 2012. [on line] . | Link |
  60. Carter EJ, Pouch SM, Larson EL. Common infection control practices in the emergency department: a literature review. Am J Infect Control. 2014 Sep;42(9):957-62. | CrossRef | PubMed |
  61. Donken R, van der Maas N, Swaan C, Wiersma T, Te Wierik M, Hahné S, et al. The use of tetanus post-exposure prophylaxis guidelines by general practitioners and emergency departments in the Netherlands: a cross-sectional questionnaire study. BMC Fam Pract. 2014 Jun 9;15:112. | CrossRef |
  62. Abiola AO, Omoyeni OE, Akodu BA. Knowledge, attitude and practice of hepatitis B vaccination among health workers at the Lagos State accident and emergency centre, Toll-Gate, Alausa, Lagos State. West Afr J Med. 2013 Oct-Dec;32(4):257-62. | PubMed |
  63. Alvarado OI, Suazo SV, Quinteros RV. [Analysis of the situation of occupational health in Chile]. Rev Lat Am Enfermagem. 1999 Jan;7(1):49-54. | PubMed |
  64. Melita Rodríguez A, Cruz Pedreros M, Merino JM. Burnout en profesionales de enfermería que trabajan en centros asistenciales de la octava región, Chile. Cienc y Enf. 2008;XIV (2):75-85. | Link |
  65. Garcia Maturana CA. Estrés laboral en personal de la unidad de emergencia ginecoobstétrica. Hospital Clínico Regional, Valdivia. [Tesis presentada para optar al grado de Licenciada en Obstetricia y Puericultura]. Universidad Austral de Chile, Valdivia, Chile; 2006. | Link |
  66. Guic S E, Mora O P, Rey C R, Robles G A. [Perceived work characteristics and coping strategies that predict distress among workers at primary health care centers]. Rev Med Chil. 2006 Apr;134(4):447-55. | PubMed |
  67. Ramírez A, Santibáñez C, Muñoz C, Ramírez G, Lechner V, Soto P, et al. Prevalencia y perfil del síndrome de burnout en el personal de salud de la Clínica Alemana de Puerto Varas. Revista GPU 2010; 6(2): 230-233. | Link |
  68. Muñoz Coloma M, Chailán PM. Síndrome de burnout en el equipo de salud de una unidad de cuidados intensivos, Concepción. Rev Chil Med Intens. 2013;28(1):13-18. | Link |
  69. Paravic Klijn T, Valenzuela Suazo S, Burgos Moreno M. Violencia percibida por trabajadores de atención primaria de salud. Cienc y Enf. 2004;X(2):53-65. | Link |
  70. Ceballos VásquezP, Valenzuela Suazo S, Paravic Klijn T. Factores de riesgos psicosociales en el trabajo: género y enfermería. Avances en Enfermería. 2014; XXXII(2):271-279. | Link |
  71. Sánchez M. Prevention of health risks in healthcare staff. Medwave 2004 Jul;4(6):e2790. | Link |
  72. Rojas N, Seymour C, Suárez R, Torres P. Accidentes laborales en el Hospital Clínico Universidad de Chile en el período 2003 – 2008. Rev Hosp Clín Univ Chile. 2009;20:119-26. | Link |
  73. Pérez Domínguez SA, Sánchez Aguilera PI. Riesgos ergonómicos en las tareas de manipulación de pacientes, en ayudantes de enfermería y auxiliares generales de dos unidades del Hospital Clínico de la Universidad de Chile. [Tesis para optar al grado de Licenciado en Kinesiologia]. Escuela de Kinesiología, Facultad de Medicina, Universidad de Chile; 2009. | Link |
  74. Gutiérrez Nova MA. Factores de riesgo psicosociales relacionados con estrés en los profesionales de enfermería de servicios críticos Hospital Puerto Montt. Tesis presentada para optar al grado de Licenciado en Enfermería. Valdivia, Chile; 2004. | Link |
  75. Grau Mascayano P, Departamento de Salud Ocupacional MINSAL. Una experiencia de investigación cualitativa en salud mental ocupacional. Trabajo presentado en: Seminario Internacional en Investigación, políticas y prácticas asociadas a problemas de salud mental y trabajo en Chile: una perspectiva de género. 14 y 16 de agosto 2007. | Link |
  76. Ansoleaga E. [Psychosocial stress among health care workers]. Rev Med Chil. 2015 Jan;143(1):47-55. | CrossRef | PubMed |
  77. Alvarado OI, Suazo SV, Quinteros RV. [Analysis of the situation of occupational health in Chile]. Rev Lat Am Enfermagem. 1999 Jan;7(1):49-54. | PubMed |
World Health Organization. Global strategy on occupational health for all: The way to health at work. Recommendation of the second meeting of the WHO Collaborating Centres in Occupational Health, Beijing, China,11-14 October 1994. | Link |

World Health Organization. Health workers. Health worker occupational health. who.int [on line]. | Link |

Leka S, Griffiths A, Cox T. Work Organization and stress: systematic problem approaches for employers, managers and trade union representatives / Protecting Workers’ Health Series No. 3. Geneva:WHO; 2004. | Link |

Psychosocial factors at work: Recognition and control Report of the Joint ILO/WHO Committee on Occupational Health. Ninth Session Geneva, 18-24 September, 1984. | Link |

Chakroun WO, Rejeb I, Kammoun L, Nasri A, Ghnainia T, Chaari A, Ksibi H, Chaari A, Bouaziz M, Rekik N. [Evaluation of stress among emergency staff: survey in a Tunisian emergency department]. Ann Fr Anesth Reanim. 2013 Sep;32(9):565-71. | CrossRef | PubMed |

de Quirós-Aragón MB, Labrador-Encinas FJ. Evaluación del estrés laboral y burnout en los servicios de urgencia extrahospitalaria. International Journal of Clinical and Health Psychology. 2007;7(2):323-335. | Link |

García-Izquierdo M, Ríos-Rísquez MI. The relationship between psychosocial job stress and burnout in emergency departments: an exploratory study. Nurs Outlook. 2012 Sep-Oct;60(5):322-9. | CrossRef | PubMed |

Pajonk FG, Cransac P, Müller V, Teichmann A, Meyer W. Trauma and stress-related disorders in German emergency physicians: the predictive role of personality factors. Int J Emerg Ment Health. 2012;14(4):257-68. | PubMed |

Flowerdew L, Brown R, Russ S, Vincent C, Woloshynowych M. Teams under pressure in the emergency department: an interview study. Emerg Med J. 2012 Dec;29(12):e2. | CrossRef | PubMed |

Healy S, Tyrrell M. Stress in emergency departments: experiences of nurses and doctors. Emerg Nurse. 2011 Jul;19(4):31-7. | PubMed |

Angius P, Campana G, Cattari F, Cattari M, Pirastru S, Tintori A, Serra A. [Burnout in emergency health care workers]. G Ital Med Lav Ergon. 2011 Jul-Sep;33(3 Suppl):339-42. | PubMed |

Wu H, Sun W, Wang L. Factors associated with occupational stress among Chinese female emergency nurses. Emerg Med J. 2012 Jul;29(7):554-8. | CrossRef | PubMed |

Adriaenssens J, De Gucht V, Van Der Doef M, Maes S. Exploring the burden of emergency care: predictors of stress-health outcomes in emergency nurses. J Adv Nurs. 2011 Jun;67(6):1317-28. | CrossRef | PubMed |

Miret C, Martínez-Larrea A.. [The professional in emergency care: aggressiveness and burnout]. An Sist Sanit Navar. 2010;33 Suppl 1:193-201. | PubMed |

Okada N, Ishii N, Nakata M, Nakayama S. Occupational stress among Japanese emergency medical technicians: Hyogo Prefecture. Prehosp Disaster Med. 2005 Mar-Apr;20(2):115-21. | PubMed |

McPherson S, Hale R, Richardson P, Obholzer A. Stress and coping in accident and emergency senior house officers. Emerg Med J. 2003 May;20(3):230-1. | PubMed |

Gillespie M, Melby V. Burnout among nursing staff in accident and emergency and acute medicine: a comparative study. J Clin Nurs. 2003 Nov;12(6):842-51. | PubMed |

Cicchitti C, Cannizzaro G, Rosi F, Maccaroni R, Menditto VG. [Burnout syndrome in pre-hospital and hospital emergency. Cognitive study in two cohorts of nurses]. Recenti Prog Med. 2014 Jul-Aug;105(7-8):275-80. | CrossRef | PubMed |

Escribà-Agüir V, Martín-Baena D, Pérez-Hoyos S. Psychosocial work environment and burnout among emergency medical and nursing staff. Int Arch Occup Environ Health. 2006 Nov;80(2):127-33. | PubMed |

Casado Moragóna A, Muñoz Durána G, Ortega González N, Castellanos Asenjob A. [Burnout in professionals belonging to palliative, intensive care and emergency services in a general hospital]. Med Clin (Barc). 2005 Apr 16;124(14):554-5. | PubMed |

Reynard K, Brown R. A clinical analysis of the emergency medicine workforce crisis. Br J Hosp Med (Lond). 2014 Nov;75(11):612-6. | CrossRef | PubMed |

Merchant RC, Becker BM, Mayer KH, Fuerch J, Schreck B. Emergency department blood or body fluid exposure evaluations and HIV postexposure prophylaxis usage. Acad Emerg Med. 2003 Dec;10(12):1345-53. | PubMed |

Marcus R, Culver DH, Bell DM, Srivastava PU, Mendelson MH, Zalenski RJ, et al. Risk of human immunodeficiency virus infection among emergency department workers. Am J Med. 1993 Apr;94(4):363-70. | PubMed |

Kelen GD. Human immunodeficiency virus and the emergency department: risks and risk protection for health care providers. Ann Emerg Med. 1990 Mar;19(3):242-8. | PubMed |

Mashoto KO, Mubyazi GM, Makundi E, Mohamed H, Malebo HM. Estimated risk of HIV acquisition and practice for preventing occupational exposure: a study of healthcare workers at Tumbi and Dodoma Hospitals, Tanzania. BMC Health Serv Res. 2013 Sep 30;13:369. | CrossRef | PubMed |

De Carli G, Puro V, Binkin NJ, Ippolito G. Risk of human immunodeficiency virus infection for emergency department workers. Italian Study Group on Occupational Risk of HIV Infection. J Emerg Med. 1994 Nov-Dec;12(6):737-44. | PubMed |

Kato-Maeda M, Ponce-de-León S, Sifuentes-Osornio J, Rangel-Frausto MS, Calva-Mercado J, Infante-Surez L, et al. Bloodborne viral infections in patients attending an emergency room in Mexico City: estimate of seroconversion probability in healthcare workers after an occupational exposure. Infect Control Hosp Epidemiol. 2000 Sep;21(9):600-2. | PubMed |

Marcus R, Srivastava PU, Bell DM, McKibben PS, Culver DH, Mendelson MH, Zalenski RJ, Kelen GD. Occupational blood contact among prehospital providers. Ann Emerg Med. 1995 Jun;25(6):776-9. | PubMed |

Galíndez L, Rodríguez Y. Riesgos Laborales de los Trabajadores de la Salud (Editorial). Salud de los Trabajadores. 2007;15(1):67-69. | Link |

arsi D, Zare MA, Hassani SA, Abbasi S, Emaminaini A, Hafezimoghadam P, Rezai M. Prevalence of occupational exposure to blood and body secretions and its related effective factors among health care workers of three Emergency Departments in Tehran. J Res Med Sci. 2012 Jul;17(7):656-61. | PubMed |

Sokolove PE, Mackey D, Wiles J, Lewis RJ. Exposure of emergency department personnel to tuberculosis: PPD testing during an epidemic in the community. Ann Emerg Med. 1994 Sep;24(3):418-21. | PubMed |

El Sayed M, Kue R, McNeil C, Dyer KS. A descriptive analysis of occupational health exposures in an urban emergency medical services system: 2007-2009. Prehosp Emerg Care. 2011 Oct-Dec;15(4):506-10. | CrossRef | PubMed |

Baydin A, Erenler AK. Workplace violence in emergency department and its effects on emergency staff. Int J Emerg Ment Health. 2014;16(2):288-90. | PubMed |

Fernandes CM, Bouthillette F, Raboud JM, Bullock L, Moore CF, Christenson JM, Grafstein E, Rae S, Ouellet L, Gillrie C, Way M. Violence in the emergency department: a survey of health care workers. CMAJ. 1999 Nov 16;161(10):1245-8. | PubMed |

Hinsenkamp M. Violence against healthcare workers. Int Orthop. 2013 Dec;37(12):2321-2. | CrossRef | PubMed |

Lancman S, Mângia EF, Muramoto MT. Impact of conflict and violence on workers in a hospital emergency room. Work. 2013;45(4):519-27. | CrossRef | PubMed |

Ferns T. Violence in the accident and emergency department--an international perspective. Accid Emerg Nurs. 2005 Jul;13(3):180-5. | PubMed |

Magnavita N, Heponiemi T. Violence towards health care workers in a Public Health Care Facility in Italy: a repeated cross-sectional study. BMC Health Serv Res. 2012 May 2;12:108. | CrossRef | PubMed |

Barnekow-Bergkvist M, Aasa U, Angquist KA, Johansson H. Prediction of development of fatigue during a simulated ambulance work task from physical performance tests. Ergonomics. 2004 Sep 15;47(11):1238-50. | PubMed |

Aasa U, Angquist KA, Barnekow-Bergkvist M. The effects of a 1-year physical exercise programme on development of fatigue during a simulated ambulance work task. Ergonomics. 2008 Aug;51(8):1179-94. | CrossRef | PubMed |

Miranda H, VViikari-Juntura E, Punnett L, Riihimäki H.. Occupational loading, health behavior and sleep disturbance as predictors of low-back pain. Scand J Work Environ Health. 2008 Dec;34(6):411-9. | PubMed |

Sorour AS, El-Maksoud MM. Relationship between musculoskeletal disorders, job demands, and burnout among emergency nurses. Adv Emerg Nurs J. 2012 Jul-Sep;34(3):272-82. | CrossRef | PubMed |

Kinoshita H, Hirose Y, Tanaka T, Yamazaki Y. Oral arsenic trioxide poisoning and secondary hazard from gastric content. Ann Emerg Med. 2004 Dec;44(6):625-7. | PubMed |

West AC, Bechtold DA. The cost of circadian desynchrony: Evidence, insights and open questions. Bioessays. 2015 Jul;37(7):777-88. | CrossRef | PubMed |

Kamdar BB, Tergas AI, Mateen FJ, Bhayani NH, Oh J. Night-shift work and risk of breast cancer: a systematic review and meta-analysis. Breast Cancer Res Treat. 2013 Feb;138(1):291-301. | CrossRef | PubMed |

Wang F, Yeung KL, Chan WC, Kwok CC, Leung SL, Wu C, et al. A meta-analysis on dose-response relationship between night shift work and the risk of breast cancer. Ann Oncol. 2013 Nov;24(11):2724-32. | CrossRef | PubMed |

Ijaz S, Verbeek J, Seidler A, Lindbohm ML, Ojajärvi A, Orsini N, et al. Night-shift work and breast cancer--a systematic review and meta-analysis. Scand J Work Environ Health. 2013 Sep 1;39(5):431-47. | PubMed |

Rabstein S, Harth V, Pesch B, Pallapies D, Lotz A, Justenhoven C, et al. Night work and breast cancer estrogen receptor status--results from the German GENICA study. Scand J Work Environ Health. 2013 Sep 1;39(5):448-55. | PubMed |

Megdal SP, Kroenke CH, Laden F, Pukkala E, Schernhammer ES. Night work and breast cancer risk: a systematic review and meta-analysis. Eur J Cancer. 2005 Sep;41(13):2023-32. | PubMed |

Jia Y, Lu Y, Wu K, Lin Q, Shen W, Zhu M, Huang S, Chen J. Does night work increase the risk of breast cancer? A systematic review and meta-analysis of epidemiological studies. Cancer Epidemiol. 2013 Jun;37(3):197-206. | CrossRef | PubMed |

Wang F, Zhang L, Zhang Y, Zhang B, He Y, Xie S, et al. Meta-analysis on night shift work and risk of metabolic syndrome. Obes Rev. 2014 Sep;15(9):709-20. | CrossRef | PubMed |

Organización Internacional del Trabajo, Consejo Internacional de Enfermeras, Organización Mundial de la Salud, Internacional de Servicios Públicos. Directrices marco para afrontar la violencia laboral en el sector de la salud. Ginebra, Organización Internacional del Trabajo; 2002. | Link |

World Health Organization. Post-exposure prophylaxis to prevent HIV infection: joint WHO/ILO guidelines on post-exposure prophylaxis (PEP) to prevent HIV infection. ISBN 978 92 4 159637 4 (NLM classification: WC 503.6); 2007. | Link |

World Health Organization. Guiding principles to ensure injection device security. Safe Injection Global Network (SIGN) Secretariat. Department of Essential Health Technologies. WHO;2012. | Link |

Hassan TB. Sustainable working practices and minimizing burnout in emergency medicine. Br J Hosp Med (Lond). 2014 Nov;75(11):617-9. | CrossRef | PubMed |

Hassan TB, Walker B, Harrison M, Rae F. Stretched to the limit. A survey of Emergency Medicine consultants in the UK. The College of Emergency Medicine. October; 2013. | Link |

World Health Organization. Workers’ health: global plan of action. Geneva: WHO; 2007. | Link |

Instituto de Salud Pública, Ministerio de Salud, Gobierno de Chile. Agentes Biológicos. Ispch.cl [on line]. | Link |

Departamento de Salud Ocupacional, Subsecretaria de Salud Pública, Ministerio de Salud, Chile. Protocolos de vigilancia para trabajadores expuestos a factores de riesgo de trastornos musculoesqueléticos de extremidades superiores relacionados con el trabajo. División de políticas públicas saludables y promoción. Departamento De Salud Ocupacional. Santiago-Chile 2012. [on line] . | Link |

Carter EJ, Pouch SM, Larson EL. Common infection control practices in the emergency department: a literature review. Am J Infect Control. 2014 Sep;42(9):957-62. | CrossRef | PubMed |

Donken R, van der Maas N, Swaan C, Wiersma T, Te Wierik M, Hahné S, et al. The use of tetanus post-exposure prophylaxis guidelines by general practitioners and emergency departments in the Netherlands: a cross-sectional questionnaire study. BMC Fam Pract. 2014 Jun 9;15:112. | CrossRef |

Abiola AO, Omoyeni OE, Akodu BA. Knowledge, attitude and practice of hepatitis B vaccination among health workers at the Lagos State accident and emergency centre, Toll-Gate, Alausa, Lagos State. West Afr J Med. 2013 Oct-Dec;32(4):257-62. | PubMed |

Alvarado OI, Suazo SV, Quinteros RV. [Analysis of the situation of occupational health in Chile]. Rev Lat Am Enfermagem. 1999 Jan;7(1):49-54. | PubMed |

Melita Rodríguez A, Cruz Pedreros M, Merino JM. Burnout en profesionales de enfermería que trabajan en centros asistenciales de la octava región, Chile. Cienc y Enf. 2008;XIV (2):75-85. | Link |

Garcia Maturana CA. Estrés laboral en personal de la unidad de emergencia ginecoobstétrica. Hospital Clínico Regional, Valdivia. [Tesis presentada para optar al grado de Licenciada en Obstetricia y Puericultura]. Universidad Austral de Chile, Valdivia, Chile; 2006. | Link |

Guic S E, Mora O P, Rey C R, Robles G A. [Perceived work characteristics and coping strategies that predict distress among workers at primary health care centers]. Rev Med Chil. 2006 Apr;134(4):447-55. | PubMed |

Ramírez A, Santibáñez C, Muñoz C, Ramírez G, Lechner V, Soto P, et al. Prevalencia y perfil del síndrome de burnout en el personal de salud de la Clínica Alemana de Puerto Varas. Revista GPU 2010; 6(2): 230-233. | Link |

Muñoz Coloma M, Chailán PM. Síndrome de burnout en el equipo de salud de una unidad de cuidados intensivos, Concepción. Rev Chil Med Intens. 2013;28(1):13-18. | Link |

Paravic Klijn T, Valenzuela Suazo S, Burgos Moreno M. Violencia percibida por trabajadores de atención primaria de salud. Cienc y Enf. 2004;X(2):53-65. | Link |

Ceballos VásquezP, Valenzuela Suazo S, Paravic Klijn T. Factores de riesgos psicosociales en el trabajo: género y enfermería. Avances en Enfermería. 2014; XXXII(2):271-279. | Link |

Sánchez M. Prevention of health risks in healthcare staff. Medwave 2004 Jul;4(6):e2790. | Link |

Rojas N, Seymour C, Suárez R, Torres P. Accidentes laborales en el Hospital Clínico Universidad de Chile en el período 2003 – 2008. Rev Hosp Clín Univ Chile. 2009;20:119-26. | Link |

Pérez Domínguez SA, Sánchez Aguilera PI. Riesgos ergonómicos en las tareas de manipulación de pacientes, en ayudantes de enfermería y auxiliares generales de dos unidades del Hospital Clínico de la Universidad de Chile. [Tesis para optar al grado de Licenciado en Kinesiologia]. Escuela de Kinesiología, Facultad de Medicina, Universidad de Chile; 2009. | Link |

Gutiérrez Nova MA. Factores de riesgo psicosociales relacionados con estrés en los profesionales de enfermería de servicios críticos Hospital Puerto Montt. Tesis presentada para optar al grado de Licenciado en Enfermería. Valdivia, Chile; 2004. | Link |

Grau Mascayano P, Departamento de Salud Ocupacional MINSAL. Una experiencia de investigación cualitativa en salud mental ocupacional. Trabajo presentado en: Seminario Internacional en Investigación, políticas y prácticas asociadas a problemas de salud mental y trabajo en Chile: una perspectiva de género. 14 y 16 de agosto 2007. | Link |

Ansoleaga E. [Psychosocial stress among health care workers]. Rev Med Chil. 2015 Jan;143(1):47-55. | CrossRef | PubMed |

Alvarado OI, Suazo SV, Quinteros RV. [Analysis of the situation of occupational health in Chile]. Rev Lat Am Enfermagem. 1999 Jan;7(1):49-54. | PubMed |